Prospective Follow-up Studyによる本邦糖尿病患者の予後調査--登録後2年目の成績,とくに糖尿病患者の原死因について
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Although it has been said that ischemic heart disease as cause of death is increasing among Japanese diabetics with the changing dietary habits of the Japanese people, there are few prospective studies dealing with the causes of death of Japanese diabetics visiting diabetes clinics. To assess the increase in ischemic heart disease as a cause of death in Japanese diabetics, we undertook a prospective follow-up study of 1, 629 diabetic patients (898 males, 731 females) who had visited our Diabetes Center in 1976. In the present paper, we describe the results of a two-year follow-up study, especially regarding the underlying causes of death in Japanese diabetics.<BR>During this follow-up study, only one case dropped out within two years from the start. The deaths of 70 cases (52 males, 18 females) among the 1, 629 were confirmed at the end of the twoyear follow-up. We obtained death certificates for all the 70 deceased patients and decided the underlying causes of death according to the eighth revision of ICD.<BR>The main underlying causes of death in the present study were malignant neoplasms (21), ischemic heart disease (17), diabetes mellitus (11), cerebrovascular disease (7) and other causes (14). The increase in rate of malignant neoplasms and ischemic heart disease as underlying causes of death among Japanese diabetics was confirmed.<BR>Analysis by comparison of the observed number of deaths with that expected for the sex-and agespecific rates of the general population over the same period of time, showed a significant excess in deaths from diabetes mellitus and ischemic heart disease in the patients of the study sample. Although 0.8 deaths attributable to diabetes mellitus were expected among the patients of the study sample, 11 deaths actually occurred: 3.8 deaths from ischemic heart disease were expected, whereas 17 actually occurred. No significant differences between observed and expected numbers of death were found for malignant neoplasms, cerebrovascular disease and other causes of death.<BR>Many deceased cases from ischemic heart disease were found in the group whose death was onfirmed from copies of the residence or census register. Autopsy was performed in only 24.3% of the deceased cases, and 74.3% of the 70 deceased cases died at hospitals. Mention of the diagnosis of diabetes mellitus was found in only 38.6% of the death certificates of the deceased diabetics.
- 一般社団法人 日本糖尿病学会の論文
一般社団法人 日本糖尿病学会 | 論文
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