Lipid Peroxide in the Plasma of Diabetics
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概要
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The lipid peroxide in the plasma of 103 diabetic patients and 331 control subjects was measured by a fluorometric method using thiobarbituric acid.<BR>1) The plasma lipid peroxide values of diabetics (5.48 ±0.76 nmole/m<I>l</I>) were significantly (P<0.001) higher than those of controls (3.74 ±0.13 nmole/m<I>l</I>).<BR>2) The plasma lipid peroxide levels were higher (P<0.001) in poorly controlled diabetics (6.39±1. 21 nmole/m<I>l</I>) than those in well controlled diabetics (4.08 ±0.38 nmole/m<I>l</I>). However, no significant correlation between plasma lipid peroxide values and glucose tolerance was found.<BR>3) The plasma lipid peroxide levels had no relation with hypertriglyceridemia and hypercholesterolemia.<BR>4) The plasma lipid peroxide values were significantly (P<0.001) higher in diabetics with angiopathy (7.69 ± 1.65 nmole/m<I>l</I>) than those without angiopathy (3.89 ±0.55 nmole/m<I>l</I>).<BR>The above results suggest that lipid peroxide plays an important role in the occurrence and progression of angiopathy in diabetics.
- 一般社団法人 日本糖尿病学会の論文
一般社団法人 日本糖尿病学会 | 論文
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