A Case of Allergic Granulomatous Angitis with Buccal Swelling.
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概要
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Allergic granulomatosis and angitis, first reported in 1951 by Churg and Strauss, were described as being distinguishable from periarteritis nodosa, since the patients had multiple systemic disease. Allergic granulomatosis and angitis were called allergic granulomatous angitis (AGA) by Zeek. AGA is characterized by certain clinical and histopathological features, i.e., asthma, eosinophilia, and systemic angitis. In this report, we described clinical and pathological findings in a case of AGA following asthma which improved adrenocortical steroid administration.<BR>The patient was a 55 year-old man with a one-month history of bronchial asthma. On July 3, 1990, he was hospitalized because of diffuse swelling in his left buccal region without improving symptoms even with antibacterial medicine administration. AGA was diagnosed on the basis of laboratory findings (WBC count; 7800/mm<SUP>3</SUP>, eosinophils; 19%) and biopsy of the specimen. Following administration of adrenocortical steroid, his condition improved, and the subsequent clinical course has remained relatively stable.<BR>The prognosis for AGA was comparatively bad, and it was conceivable that early steroid therapy for an early diagnosis like this case was important, because the occurrence age of bronchial asthma and systemic angitis is high in recurrence and death cases in comparison with complete remission cases. It is thought that the eosinophil cationic protein in activated eosinophils is related to the formation of the granulomatous lesion characteristic of AGA.
- 特定非営利活動法人 日本口腔科学会の論文
特定非営利活動法人 日本口腔科学会 | 論文
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