Ewing's sarcoma originated from zygomatic bone; Report of a case.
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Malignant small round cell bone tumors are often difficult to definitively distinguish by light microscopy alone. The present case is a rare Ewing's sarcoma that originated from the zygomatic bone. The patient, a 42-years-old man, was admitted with complaints of swelling and spontaneous pain in the left zygomatic region. Radiologic examination revealed the highly destructive zygomatic bone and maxilla involved by tumor filled in infratemporal fossa. Partial maxillectomy was performed after irradiation and chemotherapy treatments. No sign of recurrence has been seen.<BR>Surgically removed specimen was whitish with gelatinous cut surfaces. Histological examination revealed a non-encapsulated tumor with adjacent periosteal new bone. The small and round tumor cells had a scant and faintly eosinophilic cytoplasm with PAS-positive glycogen granules containing round or oval nucleus having coarse or fine granular chromatins. The tumor cells showed an invasive proliferation forming rosette-like figures. The immunohistochemical analysis showed positivity for vimentin, fibronectin, neurofilament and neuronspecific enolase. Electron microscopic examination confirmed the tumor cells possessed nuclei with finely divided chromatins and cytoplasms with abundant glycogen. Moreover, intercellular connections of desmosomal type were infrequently observed. These results supported the neuroectodermal origin of Ewing's sarcoma.
- 特定非営利活動法人 日本口腔科学会の論文
特定非営利活動法人 日本口腔科学会 | 論文
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