Two cases of Apert syndrome.
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概要
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Apert syndrome is a rare craniosynostotic syndrome characterized by acroce - phaly and syndactyly of the hands and feet. The authors report two cases of Apert syndrome with review of literature regarding oral and maxillofacial findings.<BR>First case; A 26-year-old man visited the left molar area of his mandible caused by a cystic lesion. The patient showed some features peculiar to Apert syndrome ; acrocephaly, maxillary hypoplasia, mandibular prognathism, hypertelorism, exophtalmus and so on, and further examinations led to a diagnosis of atypical Apert syndrome.<BR>Second case; A 13-year-old girl consulted us about a phonetic problem. She had an unsuccessfully treated cleft palate and showed cranio-facial anomalies, symmetric syndactylia, club foot, anomalies in teeth position and mental deficiency. A diagnosis of Apert syndrome was made, but her parents refused any treatment except teeth extraction
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