Microbiological Characterization of Clinical Isolates of Staphylococcus epidermidis.
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概要
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As a result of recent development in medical practice including use of new antimicrobial agents, coagulase-negative Staphylococci (CNS) that were once considered nonpathogenic contaminants have captured attention as causes of disease. The 43 clinical isolates of <I>Staphylococcus epidermidis sensu stricto</I> and 7 isolates of <I>S. epidermidis</I> from the medical staffs were characterized with regard to (1) their biochemical profiles, (2) slime productivity, (3)β-lactamase productivity and (4) plasmid patterns. Most of the isolates have an identical biochemical profile code. The slime production was observed in the 9 strains isolated from pleural effusions or the tubes used for pleural drainage. These strains had a similar antimicrobial susceptibility profile that are commonly seen in multi-resistant strains of methicillin-resistant <I>Staphylococcus aureus</I> (MRSA). In addition, most of these strains produced β-lactamase. For the plasmid profiling, we selected 12 isolates that possessed 5 distinct antimicrobial susceptibility profiles. Upon agarose gel electrophoresis, 8 isolates were shown to possess a 1.9 kb plasmid. These 8 isolates had resistance against tobramycin (TOB) and erythromcin (EM). Emergence of <I>S. epidermidis</I> as causes of disease will increasingly necessitate the detailed microbiological characterization of the clinical isolates.
- The Japanese Association for Infectious Diseasesの論文
The Japanese Association for Infectious Diseases | 論文
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