An outbreak of gastroenteritis possibly caused by Escherichia coli O167:H9.
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概要
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An outbreak of gastroenteritis involving a total of 256 patients (49.7%) among 515 persons occurred at a primary and secondary school in Agatsuma Town, Gunma Prefecture between the 23rd and 28th of June 1988. The majority of the cases occurred within the first 4 days. The main symptoms were abdominal pain (81.6%), diarrhea (57.0%) and headache (40.2%). In most cases, the stools were watery and occasionally mucous. Although food-borne infection was strongly suggested epidemiological evidence did not incriminate any foods as the cause of the outbreak.<BR>In the bacteriological study on stool specimens from 25 patients, <I>Escherichia coli</I> 0167: H9 was isolated from 20 of these specimens, virtually in pure culture. The isolates of the <I>E. coli</I> serovar were negative for recognized diarrheagenic virulence properties: production of heat-labile and heat-stable enterotoxins, enteroinvasion, and production of Shiga-like toxin. When the HEp-2 cell-adherence test was used, however, they exhibited localized adherence. All the strains were demonstrated to carry 56 Md plasmids that presumably mediate the production of the adherence factor.
- The Japanese Association for Infectious Diseasesの論文
The Japanese Association for Infectious Diseases | 論文
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