Vibrio parahaemolyticus infectious disease cased by Kanagawa phenomenon-negative O3:K6 originated from maldives.
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概要
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A total of 1, 393 patients with traveller's diarrhoea were examined at Osaka Airport Quarantine station from January to December in 1985. Among them, Kanagawa phenomenon-negative <I>V. parahaemolyticus</I> O3: K6 was isolated with considerable frequency from patients who had visited Maldives.<BR>The bacteriological and epidemiological study on the organism revealed the following features:<BR>1) <I>Vibrio partahaemolyticus</I> was isolated from 23.5% of the patients who had visited Maldives. As much as 911% of such <I>V. parahaemolyticus</I> isolates did not exhibit Kanagawa phenomenon. The serovars of the Kanagawa phenomenon-negative strains were all O3: K6. They did not produce the thermostable direct hemolysin detectable by an ELISA assay and did not posesses the gene encoding the hemolysin.<BR>2) The Kanagawa phenomenon-negative isolates were indistinguishable from Kanagawa phenomenon-positive <I>V. parahaemolyticus</I> by biochemical characteristics and drug sensitivities.<BR>3) All the Kanagawa phenomenon-negative isolates tested induced fluid accumulation in rabbit ileal loops:<BR>4) The main symptoms of the patients were severe diarrhoea with waterly stool, abdominal pain, vomiting, and no fever.<BR>5) The organism was isolated between May and July. and it's source was suspected to be fresh sea foods in Maldives.
- The Japanese Association for Infectious Diseasesの論文
The Japanese Association for Infectious Diseases | 論文
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