Studies on Chlamydia trachomatis as the cause of respiratory infections. I Prevalence of serum antibodies to Chlamydia trachomatis in healthy adults and patients with respiratory infections.:I. Prevalence of Serum Antibodies to Chlamydia trachomatis in He
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The prevalence of serum antibodies to <I>Chlamydia trachomatis</I> and <I>Chlamydia psittaci</I> were determined using the microplate immunofluorescence antibody technique (MFA), an indirect immunofluorescence antibody test, from 100 serum samples from healthy adults, 158 samples from patients with upper respiratory tract infection and 90 samples from patients with pneumonia.<BR>In the 100 serum samples collected from healthy adults, titer levels against <I>C. psittaci</I> were higher than 1: 8 in 4 (4.0%) and against <I>C. trachomatis</I> in 5 (5.0%).<BR>In the 158 serum samples collected from patients with upper respiratory tract infection, titer levels against <I>C. psittaci</I> were higher than 1: 8 in 14 (8.9%) and against <I>C. trachomatis</I> in 31 (19.6%).<BR>A significant difference was observed in the prevalence of antibodies to <I>C. trachomatis</I> between the patients with upper respiratory tract infection (19.6%) and healthy adults (5.0%) (p<0.001).<BR>In the 90 serum samples collected from patients with pneumonia, titer levels against <I>C.psittaci</I> were higher than 1: 8 in 5 (5.6%) and against <I>C. trachomatis</I> in 12 (13.3%).<BR>A significant difference was observed in the prevalence of antibodies to <I>C.trachomatis</I> between the patients with pneumonia (13.3%) and healthy adults (5.0%) (p<0.05).<BR>These results suggest that some pulmonary infectious diseases in adults may be caused by <I>C. trachomatis</I>.
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The Japanese Association for Infectious Diseases | 論文
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