A report of amoebiasis as an opportunistic infection.
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概要
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Two cases of amoebiasis which were considered to have been precipitated and aggreviated by pregnancy, and the administration of anticancer drugs and corticosteroid, respectively, are reported.<BR>Case I: In July 1984, a 30 year-old woman in her 15th week of pregnancy was diagnosed as a carrier of <I>Entamoeba histolytica</I> and was subsequently admitted to the Department of Infectious Diseases at the Tokyo Metropolitan Komagome Hospital. She had a history of travel to tropical and subtropical countries in the previous year, and suddenly experienced clinical symptoms of amoebic colitis including the passage of melena three times a day. The stool was positive for the trophozoite of <I>E. histolytica</I> and she was treated with 2 grams of oral metronidazole for 10 days with complete recovery.<BR>Case II: A 67 year-old woman who was diagnosed with breast cancer complicated by a right-sided carcinomatous pleuritis, was admitted to the Department of Surgery, Tokyo Metropolitan Komagome Hospital on April 1981. The radioisotopic liver scan was normal. She was treated with oral cyclophosphamide and intrapleural and selective intraarterial administration of adriamycin, experienced marked improvement. One month after treatment was initiated she became pyrexic and continued fevers up to 39°C, and experienced anal pain, melena, right upper abdominal pain, enlargement of the liver. The serum alkaline phosphatase titer was elevated and a tentative diagnosis of liver metastasis was made. Prednisolone was given, however, her condition rapidly deteriorated and she died of bacteremic shock. Autopsy revealed multiple metastases of the breast cancer, an amoebic liver abscess and amoebic colitis which had perforated, thereby spilling fecal content into the peritoneal cavity.
- The Japanese Association for Infectious Diseasesの論文
The Japanese Association for Infectious Diseases | 論文
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