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- 論文の詳細を見る
As a rapid method of diagnosis of bacterial infections, co-agglutination (CoA), latex agglutination (LA) and counter immunoelectrophoresis (CIE) were tested in order to detect the capsul antigens of pneumococcus and <I>H.influenzae</I> in specimens from patients.<BR>A comparative study with these three serological tests showed that CoA test was four to thirty-two times sensitive as LA and CIE.<BR>From 136 specimens of cerebrospinal fluid (CSF), two cases of meningitidis purulenta demonstrated <I>H.influenzae</I> and <I>pneumococcus</I> respectively by both serological and conventional methods. In the case of pneumococcal meningitidis, the antigen was detected by CoA and LA during two days after chemotherapy commenced, although negative results were obtained by the conventional method.<BR>From 97 sputum specimens, capsul antigens were detected by CoA and LA in 16 specimens; especially CoA tests were positive for <I>H.influenzae</I> type b in two cases, for <I>H. influenzae</I> type a, c-f in seven cases and for pneumococcal antigens in 11 cases, whereas nine antigen were detected by LA test.<BR>Positive CIE test was seen in only two clinical specimens; CSF from <I>H. influenzae</I> type b meningitis and sputum from pneumococcal pneumoniae.<BR>CoA test was found to be a useful tool for a rapid diagnosis of these bacterial infections as compared with other serological tests such as LA and CIE for detection of <I>pneumococcus</I> and <I>H.influenzae</I> antigens on clinical specimens.
- The Japanese Association for Infectious Diseasesの論文
The Japanese Association for Infectious Diseases | 論文
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