Intraocular Pressure Waves with Exposure to Pulsed Nd:YAG Laser, the Second and the Third Harmonics.
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概要
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To obtain useful data for establishing safety criteria for use of a pulsed Nd:YAG laser, intraocular pressure waves induced by radiating fundamental mode-Nd:YAG laser pulses (λ=1, 064nm), the second (λ=532nm), and the third (λ=355nm) harmonics were investigated. The radiation was delivered to extracted bovine eyeballs at various energies. Intraocular pressure waves generated were detected using a piezoelectric-type pressure sensor in the vitreum. Although the peak pressure increased with increased radiation energy at all wavelengths, there was a specific point on the radiation energy-peak pressure curve in the cases of the fundamental mode and the second harmonic above which the increasing rate of the peak pressure slowed. Retinal disruption was observed at radiation energies above this point. This result suggests that the specific point relates to the retinal optical breakdown threshold. In cyclic exposure tests under varied radiation energy above this point, the peak pressure at the second exposure decreased to about one-tenth of that at first exposure, and there was no significant change in peak pressure after the third exposure. This suggests that serious disruption of the retina and choroid in the focal region can be caused by only one exposure. In the case of exposure to the third harmonic, no change in peak pressure under the cyclic exposure tests and no retinal disruption were observed.
- 一般社団法人 日本生体医工学会の論文
一般社団法人 日本生体医工学会 | 論文
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