A Case of Superior Vena Cava Syndrome with Down-Regulation of Platelet Glycoprotien Ib/IX by Thrombolytic Therapy
スポンサーリンク
概要
- 論文の詳細を見る
A 51-year-old male patient with Behcet syndrome was found by venography to be complicated with superior vena cava syndrome. Flow cytometrical analysis revealed that the patient's platelet surface glycoprotein (GP) Ib and GPIX were decreased by 40 and 10%, respectively, after administration of 80, 000 U/body weight kg of urokinase. The decrease in the total platelet GPIb was confirmed by quantitative immunoblotting. The patient's plasma concentration of glycocalicin increased after administration of urokinase. In contrast, the patient's platelet surface GPIIb/IIIa were not changed after urokinase therapy. These results suggest that administration of urokinase caused proteolysis of the circulating platelet surface GPIb/IX molecules.
- 一般社団法人 日本血栓止血学会の論文
一般社団法人 日本血栓止血学会 | 論文
- 日本人のＡＤＡＭＴＳ１３
- Infection of specific strains of Streptococcus mutans exacerbated intracerebral hemorrhage
- Transcriptional regulation of megakaryopoiesis and thrombopoiesis
- 新規血小板活性化受容体ＣＬＥＣ－２ その発見から今後の展望まで:その発見から今後の展望まで
- １．臨床血栓止血学オーバービュー