Plasma endotoxin levels in liver cirrhotic rats.
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概要
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Experimental liver cirrhosis was made in Donryu rats by intraperitoneal administration of thioacetamide. Blood coagulation and fibrinolysis factors of the liver cirrhosis group were lower than those of the normal liver group and liver cirrhotic findings were also histopathologically observed. Plasma endotoxin levels were higher in the liver cirrhosis group than in the normal liver group. But, there was no significant difference in endotoxin levels of inferior vena dava blood, portal vein blood and thoracic lymph duct lymph, either in the group with the liver cirrhosis group or in the normal liver group. Plasma endotoxin inactivating activity in the liver cirrhosis group was lower than that of the normal liver group. It is proposed that the decreased plasma endotoxin inactivating activity in the liver cirrhosis group is one important cause of endotoxemia.
- 一般社団法人 日本血栓止血学会の論文
一般社団法人 日本血栓止血学会 | 論文
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