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Urokinase (UK), a plasminogen activator, was immobilized on six different kinds of polymer tubes and the antithrombogenicity evaluated.89 UK-immobilized tubes were used in cases of thyroid and breast surgery and 65 non-treated PVC tubes served as the controls. Patency of the former was 93.3%, while, that of the latter was only 4.6%. Seventeen PVC-UK drains were applied to patients surgically treated for cardiac disorders and 55 usual non-treated ones were used as the controls. Milking and/or thrombectomy with Fogarty's balloon catheters was rarely necessary in the former, while, that was frequently required in the latter.
- 一般社団法人 日本血栓止血学会の論文
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