タイトル無し

概要

論文の詳細を見る
Blood viscosity at the shear-rate of 225.00sec-1, erythrocyte deformability (DI), and other variables were determined in 3 healthy subject groups: the young age group including 13 subjects with average age of 21.8 years, the middle age group 15 subjects with 53.0 years, the old age group 19 subjects with 73.7 years.In the old age group, whole blood viscosity, plasma viscosity and plasma fibrinogen concentration were significantly higher and DI, ATP and albumin level were significantly lower compared to those in the other 2 groups.Whole blood viscosity was correlated directly to hematocrit, fibrinogen concentration and fibrinogen/albumin ratio, and plasma viscosity was also correlated directly to fibrinogen concentration in the old age group.Although whole blood viscosity was correlated directly to DI in all subjects, significant correlation could not be detected in separate observation of each age group. To confirm the relationship with erythrocyte deformability, further investigation on whole blood viscosity at different shear-rates would be necessary.In the old age group, depletion of ATP and increment of fibrinogen concentration must be causative factors of hypervi scosity state.
一般社団法人日本血栓止血学会の論文