A CLINICOPATHOLOGICAL STUDY ON ELEVATED TYPES OF ADENOMAS OF THE STOMACH

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概要

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• We studied on clinicopathological features of elevated type of gastric adenomas in 161 cases (190 lesions). The endoscopic characteristic features were evaluated on 36 lesions, followed-up for 6 months or more. Fifty-five resected lesions were investigated path-ologically. On endoscopic findings, elevated adenoma was observed as normocolored or discolored in comparison with the surrounding mucosa and elevated lesions with flat or nodular surface. The shape and size of followed-up lesions was unchanged in 80.6% and also unchanged in 6 lesions (16.7%) histologically changed in biopsy specimens. From these results, most gastric adenomas are unchanged macroscopically histologically and if the macroscopic form changed, it was considered that the changes might be very slight. In histopathological study, the size of carcinoma in adenoma was significant larger than that of adenoma. Six (42.9%) of 14 lesions over 21 mm in diameter were transformed to carcinoma. Intestinal metaplastic change was recognized in 52 lesions (94.5%), exsisting in full layer of the mucosa in the surrounding mucosa. However, it was only 4 lesions (7.2%) that intestinal metaplasia mainly exsisted in the deeper layer of adenomatous tissue. In addition, cystic dilatation occupied about 20% of full thickness of the mucosa throughout the adenoma. From these results, we presumed a growing pattern of elevated adenoma, namely, the initial form of suchlesion might be flat and afterwards, protruded by cystic dilatation originating in the deeper layer of adenomatous tissue.

• 社団法人 日本消化器内視鏡学会の論文

社団法人 日本消化器内視鏡学会 | 論文

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