CLINICOPATHOLOGICAL STUDY OF GASTRIC ADENOMAS WITH SPECIAL REFERENCE TO ASSOCIATED MALIGNANCY

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We reviewed 89 gastric adenomas found in 83 patients over the past 10 years. Of these, 38 lesions in 36 patients were followed up endoscopically and histopathologically for periods ranging from 6 months to 10 years. Gastric adenomas were found more frequently in elderly male patients, and most of lesions were located in the A region. Most of lesions were of an elevated type with ha-like elevation, and were less than 2cm in diameter. Coexistence with carcinoma was seen in 70% of the adenomas more than 2cm in diameter. Adenoma coexisting with carcinoma within the same lesion was found in 6 cases. Focal cancer in adenoma, which was thought to be the result of malignant change, was found in 3 cases. During the follow up period, changes in the endoscopic appearance were observed in 10 lesions. 3 lesions increased in size and 2 of them coexisted with gastric cancer, 3 lesions decreased in size, and 4 lesions disappeared. Gastric cancer was associated in 25% of 83 cases. Adenomas, which show a gradual increase in size and are more than 2cm in diameter, are recommended strip biopsy. Even if adenomas are less than 2cm in diameter, endoscopical follow-up should be undertaken, because of the possible association with gastric cancer.
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