A morphological study of colorectal cancer and adenoma.

概要

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Fifty-two early colorectal cancers and 578 adenomas removed by polypectomy were investigated with reference to their sizes, locations and gross appearances. Three hundred twenty-two advanced cancers were also investigated with reference to their locations. The following results were obtained. (1) Early cancers were most frequently seen in the sigmoid colon. (2) Pedunculated early cancers were most frequently seen in the sigmoid colon in contrast to the subpedunculated type. (3) Similarly, pedunculated type of adenomas over 6 mm in diameter were distributed most frequently in the sigmoid colon. (4) Advanced cancers were most frequently seen in the rectum. Pedunculated type of early cancer of the large intestine seems to need longer time to develop to advanced cancer than subpedunculated type of early cancer. If all types of early cancers progress to advanced cancer equally, more numerous advanced cancers must be found in the sigmoid colon. This slow progression of pedunculated type of early cancers can explain opposite distributions of early and advanced colorectal cancers.
社団法人日本消化器内視鏡学会の論文