NON-ICTERIC PRIMARY BILIARY CIRRHOSIS : REPORT OF 5 CASES

概要

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We clinically studied five cases with non-icteric primary biliary cirrhosis (PBC). All patients were female and the mean age was fifty. Concerning laboratory findings of liver function, the serum level elevation of GOT and GPT was moderate, that of biliary tract enzymes ; Al-p, LAP and r-GTP remarkable and that of total cholesterol and IgM in various degrees. The above-mentioned pattern of liver function test continued long. Some kind of autoantibodies were detected in all cases. In five cases with PBC we performed a laparoscopy at non-icteric stage and noticed that reddish patches were seen in all cases and cholestatic findings could not be seen on the liver surface. Reddish patches were irregularshaped and distributed unevenly in comparison with red spots which are recognized in some of chronic active hepatitis. Under long-term observation of the liver function, the level of serum GOT and GPT is more stable in non-icteric PBC than chronic active hepatitis with red spots. Therefore, we think that we can distinguish non-icteric PBC from chronic active hepatitis with red spots by laparoscopy and follow-up of the liver function.
社団法人日本消化器内視鏡学会の論文