ENDOSCOPIC STUDY ON AREAE GASTRICAE OF THE FUNDIC MUCOSA
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概要
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The areae gastricae of fundic mucosa were examined on 165 cases with and without gastro-duodenal diseases by dye spraying endoscopy. Areae gastricae of fundic mucosa were classified to 4 types ; type F<SUB>0</SUB> is small and fine areas arranging closely to each other. Area of type F<SUB>1</SUB> is largest in size, round and tall. F<SUB>2</SUB> is large in size but not so tall. F<SUB>3</SUB> is small and flat areas arranging loosely to each other. Gland atrophy, f oveolar hyperplasia, intestinal metaplasia, cell infiltration and lymph follicle of biopsied specimen of each area type were studied. None or mild changes were seen in F<SUB>0</SUB>, but more severe changes were observed in order of F<SUB>1</SUB>, F<SUB>2</SUB> and F<SUB>3</SUB>. F<SUB>0</SUB> and F<SUB>1</SUB> were seen in the stomach with large fundic mucosa and F<SUB>2</SUB> and F<SUB>3</SUB> were with small fundic mucosa. F<SUB>0</SUB> and F<SUB>1</SUB> were frequently observed at the greater curvature of the middle body, center of the fundic mucosa. On the other hand F<SUB>2</SUB> and F<SUB>3</SUB> were at the lesser curvature or at near to the mucosal border. Considering the patterns of areae gastricae and histological findings, we can suspect as follows : 1) Area of Fo are formed by mechanical accomodation to the stomach movement such as peristalsis, then gradually changed to F<SUB>1</SUB>, F<SUB>2</SUB> and F<SUB>3</SUB> by inflammation, erosions and atrophic changes of the fundic mucosa and so on. 2) Atrophic changes of the fundic mucosa arise at the lesser curvature or at near to the mucosal border. As the fundic mucosa become small in extent, atrophic changes progress even to the greater curvature of the middle body in parallel with atrophic changes of the pyloric mucosa.
- 社団法人 日本消化器内視鏡学会の論文
社団法人 日本消化器内視鏡学会 | 論文
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