Hypothermia in dogs. II. The effects of controlled ventilation on the resuscitation of the heart in experimental dogs.:II. The effects of controlled ventilation on the resuscitation of the heart in experimental dogs

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A total of 24 puppies (average body weight, 3.7kg) were subjected experimentally to surface-cooling, simple hypothermia using a ventilator with a respiratory rate of 25/min. and a tidal volume of 25ml/kg, 20ml/kg, and 15ml/kg, when the esophageal temperature was 30°C. During the circulatory arrest (about 30 minutes), the chordae tendineae was experimentally ruptured and mitral vulvuloplasty was performed. From the results of PaCO2 measurements during circulatory arrests, puppies were divided into 3 groups: group I (PaCO2 10—20 mmHg), group II (PaCO2 20—30 mmHg), and group III (PaCO2 30-40 mmHg) . Group I demonstrated better result than group II or III in term of the resuscitation of the heart. The pH just before circulation arrest in group I averaged 7.529 (measured at 37°C), and its corrected value at 24°C was 7.724. The tidal volume was 25ml/kg, and the duration of the ventilation was about 40 minutes.
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