The clinical investigation of enflurane anesthesia in the dog. Preliminary report.
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The preliminary study on the clinical use of enflurane anesthesia in 16 major surgeries of the dog has shown that type of inhalation anesthesia can be successfully and safty used follwing the induction of anesthesia either by enflurane inhalation from a mask or intravenous injection of thiopental sodium.<BR>The average concentration of enflurane necessary for the maintenace of surgical stage was 2.4 percent (range: 1-3 percent) and no differance was found between two types of the induction used. After the maintenance of anesthesia as long as 95 minutes in most cases, the rapid recovery from anesthesia was obtained following the turning off of the anesthetic gas. All animals showed the pharynx-larynx reflexes within 4 minutes and started to walk after 10 minutes.<BR>Although some mild time-dependent decline of the heart rate and the body temperature were observed during the anesthesia, the mean blood pressure and respiratory rate were maintained in very constant level a little lower than the normal range. No significant effect on kidney and liver functions was found as far as the post anesthetic serial determinations of GOT, GPT, LDH, ALP, urea nitrogen and creatinine in serum are concerened, Furthermore, any neurological problems such as muscular twitching and convulsions, which have been reported to appear occasionally in some species, were not seen in either of the inductions.
- 獣医麻酔外科学会の論文
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