CLINICAL AND HEMATOLOGICAL FINDINGS DURING ELECTROACUPUNCTURAL ANALGESIA (EAA) IN THE DOG:—OBSERVATIONS IN THE COURSE OF EAA BY GRADUAL INDUCTION, AND RAPID INDUCTION WITH THIAMYLAL SODIUM PREMEDICATION—
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Six clinically healthy mongrels were used repeatedly in the following experiments.<BR>(A) Experiments of gradual induction of EAA on bilateral Sp-6 (G.I, experiments) : Load voltage was increased up to 6-7 Vp-p gradually within 60 min., and thereafter maintained for 40 min. (EAA: 5 cases, Control: 5 cases) .<BR>(B) Experiments of rapid induction of EAA on bilateral Sp-6 (R.I. experiments) : Soon after i.v, injection of thiamylal sodium 12.5 mg/kg, b.w., load voltage was increased up to 15 Vp-p within 2 min., and thereafter maintained for 60 min. (EAA: 6 cases, Control: cases) . Clinical and hematological observations were performed periodically.<BR>Results: (A) G.I. experiments<BR>1) During the induction stage dogs were excited, while they were quiet during the maintenance stage.<BR>2) Body temperature (T), pulse rate (P) and respiration rate (R) increased accompanying with the increace of load voltage, and decreased gradually during the maintenance stage.<BR>3) WBC and neutrophil (%) increased gradually.<BR>4) Plasma glucose was elevated during the induction stage, and thereafter reduced gradually.<BR>5) No distinct changes were shown in Ht values, total serum protein (TP), plasma urea-N and total cholesterol.<BR>Results: (B) R.I. experiments<BR>1) Dogs were quiet or drowsy throughout the experiment.<BR>2) In the early stage of induction, reduction of T and increase of P were observed, and thereafter T and P returned to normal gradually.<BR>3) R showed no remarkable changes.<BR>4) WBC and neutrophil (%) increased gradually.<BR>5) Plasma glucose showed transient elevation.<BR>6) No distinct changes were shown in the levels of Ht, TP, urea-N and total cholesterol.<BR>These results supported the authers' view that EAA with premedication of thiamylal sodium was recommended.
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