FUNDAMENTAL STUDIES OF ANESTHESIA ON EXPERIMENTAL INTESTINAL OBSTRUCTION IN DOGS:COMPARISON BETWEEN HALOTHANE AND ETHER INHALATION ANESTHESIA
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Experiments were performed to make comparison between the influence of Halothane (H-I) and Ether (E-I) inhalation anesthesia on experimental intestinal obstruction (upper occlusion) in dogs, at the same time intact Halothane (H-N) and Ether (E-N) inhalation anesthesia for control anesthesia were carried out.<BR>Comparison was made of clinical findings, blood pressure, blood gases and acid-base balance, blood components and body fluid.<BR>The results were as follows:<BR>1) After 96 hours of intestinal obstruction, decrease of body fluid and plasma chloride which were caused by a vomiting, at the same time increase of pulse rate, blood concentrate, hypotonia and a mild acidemia were recognized.<BR>2) In E-I group, delay of time of the laryngo-pharyngeal reflexes were observed, and 2 heads of E-I group died without a completely awaking.<BR>3) Body temperature, pulse rate and respiratory rate resulted similar effects in all groups (H-N, E-N, H-I, E-I) .<BR>4) Arterial blood pressure depressed in intestinal obstruction groups (H-I, E-I) .<BR>5) Halothane anesthesia groups (H-N, H-I) exhibited respiratory acidosis, and Ether anesthesia groups (E-N, E-I) showed mixed acidosis. Furthermore, intestinal obstruction groups (H-I, E-I) were more aggravating than control groups (H-N, E-N), particularity, E-I group maintained after the end of anesthesia.<BR>6) Ht, Hb, plasma electrolytes and osmotic pressure did not change in all groups (H-N, E-N, H-I, E-I) .<BR>7) Body fluid volume were not difference between H-I and E-I group.<BR>From these results, it is presumed that use of Halothane inhalation anesthesia was better than Ether inhalation anesthesia on intestinal obstruction in dogs.
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