タイトル無し

概要

論文の詳細を見る
A 51-year old female came with left cervical lymph node swelling which had been growing over the past year. Cervical lymph node biopsies were performed two times and the specimens demonstrated non-caseating epithelioid cell granulomas. As a result, the patient was diagnosed as having sarcoidosis. Although treatment with corticosteroid and immunosuppressants was started, the size of the cervical lesions repeatedly fluctuated from smaller to larger. Therefore, a third lymph node biopsy was performed under general anesthesia. The last biopsy specimens revealed numerous Hodgkin cells without any non-caseating epithelioid cell granulomas. The patient was thus finally diagnosed as having Hodgkin's lymphoma. The presence of noncaseating epithelioid cell granulomas in association with Hodgkin's lymphoma has been recognized (so-called sarcoid reaction). Occasionally, it may be difficult to make a correct diagnosis for Hodgkin's lymphoma in cases where the pathological findings reveal a sarcoid like reaction. This is an instructive case to consider when making a diagnosis of sarcoidosis.
日本サルコイドーシス/肉芽腫性疾患学会の論文