タイトル無し

概要

論文の詳細を見る
We investigated clinical characteristics and therapeutic outcome of nine patients with bone involvement (6 males and 3 females) out of the 416 sarcoidosis cases (2.2%) visiting our clinic during the past decade. As four of them who were undergoing no treatment showed a new bone lesion, the affected sites totaled 14: seven hand phalanxes, five metatarsus, and two foot phalanxes. Almost all bone lesions appeared in company with worsening or new manifestation of other organ lesions. The chief complaints were pain in the affected regions in eight patients and deformity of hand fingers in one. As for diagnostic procedures, bone x-rays worked satisfactorily in all but one, revealing cystic or lacy lytic patterns. Bone scintigram and/or magnetic resonance imaging were sometimes more high resolution than x-rays. When patients having affected finger bones shake hands they frequently complain of finger pain. This "handshake sign" seems useful for suspecting finger bone involvement. As for treatment, five of the nine needed corticosteroids and four of them were successfully treated in a year or so to the point of ceasing medication or minimizing the dose. As corticosteroids give relief for persistent bone pain, we need not hesitate prescribing corticosteroid for them.
日本サルコイドーシス/肉芽腫性疾患学会の論文