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The prognosis of patients with cardiac sarcoidosis has been improved by the progress of antiarrhythmic drugs, but heart failure death has been reported a lot recently as an important factor affecting prognosis. Case 1 is a 76 year old man. We noted BHL in 1993, and it was diagnosed as sarcoidosis by lung biopsy. He experienced worsening of dry cough and thoracic shadow in 1997 and was readmitted. We recognized diffuse left-ventricular wall hypokinesis by UCG and negative T wave and frequent extrasystoles in ECG, which we had not found in 1993. In this case, it was possible to evaluate cardiac activity by comparing data from the early period of the illness. Case 2 is a 74 year old woman. In 1992, in a general examination, she was first found to have a dry cough and chest abnormal shadow. It was diagnosed as sarcoidosis by skin biopsy. She experienced occasional heart palpitation from about 1996, and in 1998 was admitted as an emergency admission suffering from ventricular tachycardia and having a disturbed mind. Improvement was provided with antiarrhythmic agent, but abnormal ECG such as ST-T changes continued. We report about successive changes in ECG and Holter ECG monitoring.
日本サルコイドーシス/肉芽腫性疾患学会の論文