Clinical Study on Sarcoidosis with Splenic Involvement

概要

論文の詳細を見る
1. Peritoneoscopy and liver biopsy was performed to examine hepatic involvement of sarcoidosis that was frequently found even without hepatic dysfunction. By this procedure seven sarcoidosis patients showed multiple miliary nodules on spleen surface without hypersplenism. Follow up of outcome of these patients showed good prognosis.2. Sarcoidosis patients with SOL on abdominal CT were found in the patients older fourty with CXR stage II and III, hepatic and other extrapulmonary involvement and also elevated ACE in high frequency. Splenic involvement of sarcoidosis appeared as multiple whitish plaques and also several cuboid tumorous nodules, 1-2cm in diameter, on laparoscopy, multiple hypoechoic areas on ultrasound examination and multiple SOL on abdominal CT and MRI. SQL on abdominal CT disappeared after steroid treatment but reappeared during follow up in one case. In one of two patients who received splenectomy to rule out malignant lymphoma, lung lesion appeared on CXR during follow up. Therefore careful long term follow up study is necessary.
日本サルコイドーシス/肉芽腫性疾患学会の論文