A Case of Wegener's Granulomatosis Escaped from Blindness by Cyclophosphamide Pulse Therapy

概要

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The patient was a 45-years male who presented with low vision, pressure feeling of eyeball and excessive lacrimation.At first, he was diagnosed having chronic sinusitis, but C-ANCA was positive. After the enlargement of bilateral intraorbital mass lesion progressed, he was treated with succinic methylprednisolone pulse therapy, but his left eye became blind. Because his right corrected eye vision was also threatened, we checked the history of eyelid mass lesion in detail, and made the diagnosis of Wegener's granulomatosis. By cyclophosphamide pulse therapy and succinic acid methylprednisolone, the size of mass lesion decreased and he escaped from blindness. We know subtype of Wegener's granulomatosis that has limited lesion without kidney lesion. It is often difficult to care it. We have experienced a case who escaped blindness by cyclophsphamide pulse therapy with corticosteroid.
日本サルコイドーシス/肉芽腫性疾患学会の論文