Development of a New Method for Calibration of Pneumotachograph According to Flow Rate. Evaluation of a computer-controlled-system for assessing respiratory gas exchange using this method.

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1) We evaluated the method for calibrating the pneumotachograph according to flow rate by the software on personal computer. Flow volume was detected using the approximated equation (y = 1.294x2+0.989x+35.824, r = 0.976, p < 0.01) from various mean flow rate and integration of output voltage. The error between syringe volume (21) and the estimated value on the equation was l0d±8 ml (0.48±0.42 %). 2 ) Using the method descrived in l), we developed computer-controlled-system for assesing respiratory gas exchange by mixing chamber method.To evaluate the accuracy of the system as compared with the Douglas Bag method, we measured the gas parameters of the both methods for two male subjects at rest(3 and 5min) and steady state exercise (3 min., 60-240watt). The error between the both methods were within±5 % in ventilation(VE), mixed expired O2 (FEO2) and CO2 (FECO2) concentration, and were within±8% in O2 uptake(VO2) and CO2 production(VCO2). There were high positive correlation(r > 0.99, p < 0.01) between the both methods in the all parameters. These results indicate that the system in this stydy would be practical use, that VE can be measured in only one pneumotachograph, even if the range of flow rate was wide(e.g. from rest to heavy exercise).
日本生理人類学会の論文