Investigation of the Origin of MRSA Infection with Pulsed Field Gel Electrophoresis in the NICU
スポンサーリンク
概要
- 論文の詳細を見る
Methicillin resistant <I>Staphylococcus aureus</I> (MRSA) is one of the world's most significant nosocomial pathogens and is capable of causing a wide range of hospital infections. In Japan, carriage of MRSA is common among neonates in the Neonatal Intensive Care Unit (NICU) . Once MRSA is introduced into a hospital, it is difficult to eradicate. In order to control the spread of infection, it is necessary to identify the origin and transmission route of MRSA isolates. The aim of this study is to identify the genome type of MRSA in the NICU of Showa University Hospital to examine the extent of MRSA infections in the hospital such that infection control procedures can be implemented by hospital personnel to limit the spread of MRSA. Laboratory findings play an important role in infection control. Pulsed field gel electrophoresis (PFGE) of restriction fragments of genomic DNA was used to classify the genome type of MRSA. PFGE has the capacity to discriminate between MRSA isolates and is superior to other genotyping techniques. We analyzed 13 MRSA specimens from the NICU, from March 2006 to October 2006. Genome analysis indicated that 11 of the MRSA specimens have the same origin, while the other 2 have a different origin. This result suggests that MRSA has colonized in the NICU and is the source of infection. While conventional cleaning procedures reduce the incidence of MRSA, it is clear that MRSA can persist. Improvements are required for the control of MRSA in NICU. Surveillance of the origin and spreading of MRSA by PFGE is essential for assessment of nosocomial MRSA infection.
- 昭和大学・昭和医学会の論文
昭和大学・昭和医学会 | 論文
- 病理検体（ホルマリン固定パラフィン包埋組織切片）を用いた感染症遺伝子診断：結核菌Mycobacterium tuberculosis
- リンパ形質細胞性リンパ腫 / Waldenströmマクログロブリン血症
- 大学での30年間を振り返り
- 摂食・嚥下障害のリハビリテーションその包括的対応
- 原発性肝癌肝切除後の根治的治療不能残肝再発例に対するCDDP+5-FUによる肝動注療法の経験 : ―静止療法としての抗腫瘍効果と副作用―