Repair of Dry Skin by Minerals in Seawater: OLIGOMARINE as a Skin Moisturizer
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概要
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OLIGOMARINE® is a complex of minerals obtained from seawater. In a cell culture system, OLIGOMARINE® stimulated not only the cell activation but also the collagen synthesis of fibroblasts. In addition, OLIGOMARINE® might have accelerated the keratinization since the expression of suprabasal markers, such as involucrin and transglutaminase, were promoted in cultured normal human keratinocytes. Furthermore, the water-holding properties and permeability barrier function of the stratum corneum were enhanced by using lotion containing OLIGOMARINE®. These results suggested that OLIGOMARINE® would be useful as a humectant for the prevention or improvement of dry skin.
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