Percutaneous Absorption of Amono Acids into Human Skin In Vitro.
スポンサーリンク
概要
- 論文の詳細を見る
Five amino acids (L-lysine hydrochloride, glycine, sodium L-glutamate L-proline, and L-threonine) were used in this study. Their percutaneous absorption from pH 7.4 aqueous solution (PBS buffered saline) were investigated on human cadaver skin. The effects of glycerin, sodium PCA etc. on the absorption of L-proline were also investigated. Amino acids did not penetrate into the reservoir within a few hours but the amounts of adsorbed amino acid in stratum corneum were increased when glycerin or sodium PCA was incorporrated. A negative correlation between flux and log P (n-octand/water) was observed when the amino acid penetration into the receiver solution reached steady state. These resulls suggest not only the possibility of micro channels for amino acid permeation into human skin but also the possibility of incorporating amino acids into skin surface to subserve skin function.
- 日本化粧品技術者会の論文
日本化粧品技術者会 | 論文
- 加齢臭発生機序に基づく対処商品の開発
- ヒトのくせ毛の微細構造
- 触動作の特徴抽出による化粧品の使用感評価--スキンケア製品の塗布動作
- 新規カチオン性ポリマーの開発とその応用
- 顔面頬部位立体形状の加齢変化