Stabilization of O1+O2+.../W type emulsions.

概要

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O1+O2+…/W type emulsion, which we discuss in this article means the cream which the oil droplets with different properties such as O1 (which has a good sense for skin) and O2 (which has high mutual solubility with an active component) were dispersed.The continuous phase of O1+O2+…/W type emulsion comprises surfactant (D) phase formed by surfactant, co-surfactant (ex. fatty alcohol) and water, but it is difficult to stabilize O1+O2+…/W type because of a movement of each oil through the D phase.The miscibility between D phase and oil was investigated on the basis of D phase properties, i.e. total surfactant conc., HLB, the addition of water-soluble polymer. As a result, it was found that making the surfactant conc. as low as possible and the addition of water-soluble polymer (sodium hyaluronate, CP (934)-K) with high bound water contents were impotant factors in order to reduce the miscibility and then stabilize O1+O2+…/W type. It seems that the addition of water-soluble polymer changes hydration state of D phase, that is, makes HLB of D phase shift toward hydrophilic property.In addition, it was demonstrated that the sensual evaluation of O1+O2+…/W type emulsion was different from that of mix-oil emulsion which O1 and O2 mixed each other.Thus, it was suggested that emulsions combined both various sensual state and stable encapsulation of an active component were expected for O1+O2+…/W type.
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