The scheduled method of ovarian hyperstimulation for in vitro fertilization and embryo transfer was useful for avoiding oocyte retrieval on the weekend.
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The scheduled method of ovarian hyperstimulation for IVF-ET, in which the day of oocyte retrieval is determined in advance in order to avoid oocyte retrieval on the weekend, was evaluated and the results were compared to those obtained by the conventional method. Thirty-one cycles in patients undergoing ovarian hyperstimulation for IVF-ET were stimulated according to the scheduled method (scheduled group), and 52 cycles in patients with similar indications for IVF-ET and of a similar age were stimulated by the conventional method of ovarian hyperstimulation (conventional group). In the scheduled method, injection of FSH and hMG under a GnRHa long protocol was started 11 days before the day of oocyte retrieval. The day of oocyte retrieval was scheduled on Monday, Tuesday or Wednesday. In the conventional method, FSH and hMG under GnRHa short protocol were administered daily until the sum of the long diamater and short diameter of the second leading follicle reached 35 mm. Other procedures were similar in the two groups. Embryo transfer was conducted 48 hours after oocyte retrieval. The cancellation rates (CR), clinical pregnancy rates (PR), and day of oocyte retrieval were evaluated in the two groups. The PR in the scheduled and conventional groups were 39.1% and 13.9%, respectively (p<0.05). In 88.0% of cycles in the scheduled group, oocyte retrieval was performed on the scheduled day. The CR and the grade of embryos were comparable between the two groups. The scheduled method of ovarian hyperstimulation for IVF-ET produced good clinical results and was useful for avoiding oocyte retrieval on the weekend. [Adv Obstet Gynecol 52 (2); 115 - 119, 2000 (H.12.3)]
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