Clear cell carcinoma of the ovary: a study of 4 cases.
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We experienced four clear cell carcinomas of the ovary during the past five years. The patients were between 45 and 66 years old. The clinical stage (FIGO stage) was stage Ic in two patiants, stage IIa in one patient, and stage IV in one patient. Three patients excluding the patient who had stage IV disease are alive without evidence of disease. The patient who had stage IV disease died of disease after 5 months. The chief complaints were lower abdominal tumor in two patients, lower abdominal tumor and abdominal distention in one patient, and lower abdominal pain in one patient. We speculated that all the tumors had been malignant before the operation because of their pictorial findings. The histological findings were two papillous type, one tubulocystic type, and one solid type. All four patients received operation and adjuvant chemotherapy. Two patients were treated with CAP (CDDP+ADM+CPM) chemotherapy, one patient with EP (etoposide+CDDP), and one patient with MMC+ActD+CDDP. We speculate that the prognostic factor of the clear cell carcinoma of the ovary was influenced by its clinical stage as are other epithelial ovarian tumor, and we suggest that the chief complaints, age, pictorial findings, histological pattern had no predictive value for survival, although we experienced only four cases. We suggest that sufficient curative surgical resection without residual tumor, postoperative chemotherapy, and postoperative radiation therapy improves prognosis. [Adv obstet Gynecol 49 (1); 6 --12, 1997 (H9.1)]
- 近畿産科婦人科学会の論文
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