Artificial abortion in a patient with Romano-Ward syndrome.

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Patients with autosomal dominant long QT syndrome (Romano-Ward syndrome) are at potential risk of syncopal attacks and sudden death from ventricular arrythmia, torsade de pointes or ventricular fibrillation. Therefore, it is crucial to prevent arrythmias in such patients during pregnancy. We report a case of an artificial abortion complicated by this syndrome. The patient was a 17-year-old woman, who had never previously been pregnant and had been found to have this syndrome. Prolongation of the QT interval had been observed previously in her elder sister and younger brother. At admission, the ECG showed a prolonged QTc of 0.58 sec, without other any remarkable features, when the gestational age of the patient's fetus was 16 weeks. An artificial abortion was successfully induced using anti-arrythmic agents, after cervical dilatation with laminaria. It is suggested that such patients should be placed under intensive care throughout the gestational and perioperative period. [Adv Obstet Gynecol 48 (2); 145-148, 1996 (H8.3)]
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