A case of pregnancy complicated by adult polycystic kidney disease(APKD).

概要

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Adult polycystic kidney disease (APKD) is considered as an autosomal dominant, renal disorder characterized by slowly growing renal cysts. Since the renal cysts usually grow slowly in most of the patients, the disease doesn't become clinically manifest before adolescence. However, APKD can progress leading to renal failure in many cases. The mutual influence of APKD and pregnancy is of considerable concern when a patient becomes pregnant after manifesting APKD symptoms. We present the case of a patient in whom APKD rapidly developed with the incidence of PIH in the third trimester of pregnancy. The patient was 34 years old, GIPO. Her father, her younger sister and two uncles had APKD, and her grandfather had died of renal disease. She was admitted to hospital because premature delivery was feared and for careful examination of renal function when she entered the 26th week of gestation. Cesarean section was performed on week 37 because of rigidity of the soft birth canal. The patient delivered a healthy 2406g boy with an Apgar score of 7.
近畿産科婦人科学会の論文