Four cases of idiopathic thrombocytopenic purpura(ITP) in pregnancy.

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We report 4 cases of idiopathic thrombocytopenic purpura in pregnancy. Two were refractory to treatment with corticosteroid and responded poorly to high doses of gamma-globulin therapy. Therefore, fresh blood and/or platelet transfusion was needed to elevate the platelet count in order to lower the risk of maternal intracranial hemorrhage before and at the time of delivery. Of these two patients, one delivered artificially an extremely premature female infant at 29 weeks of gestation, and the other delivered a normal female infant by cesarean section at 37 weeks of gestation. The third patient had a spontaneous remission at 30 weeks of gestation and delivered a normal female at 38 weeks of gestation. The fourth patient conceived during a clinical remission after splenectomy and delivered a normal male infant at 39 weeks of gestation. None of the neonates were affected by neonatal thrombocytopenia.
近畿産科婦人科学会の論文