A case of endocervical squamous cell carcinoma in situ detected by cytopick method following 6 years of negative histological diagnosis.

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A case of squamous cell carcinoma in situ of the endocervix in a 58 year old menopausal woman is reported. The patient was followed up over a long period of time. She was examined several times by different methods such as colposcopy, cytology and punch biopsy over a period of six years. Cytologic examination over the entire period used cotton swab and occasionally cytobrush. Cytological classification was class III a-III b. Colposcopy as well as histology revealed no specific malignancy of the endocervix.<BR>However, by using Cytopick, squamous cell carcinoma in situ was indicated and a simple total hysterectomy was recommended. After the operation, the pathological diagnosis confirmed the cytological diagnosis.<BR>This case indicates that squamo-columnar junction after menopause may shift into cervical canal, especially near the internal os. If colposcopy, as well as punch biopsy are not applicable in this area of malignancy, then collecting cells from the endocervical canal may provide a correct diagnosis.<BR>In this case, the malignant squamous epithelial cells were only detected by Cytopick.<BR>To collect cells from the entire surface and the total area of the cervical canais by cotton swab and cytobrush is extremely difficult. Therefore Cytopick was chosen as it is the most suitable tool for this purpose.
近畿産科婦人科学会の論文