A case report of essential thrombocythemia in pregnancy.
スポンサーリンク
概要
- 論文の詳細を見る
Essential thormbocythemia is a rare myeloproliferative disorder of unknown cause characterized by elevation in platelet counts and increased marrow megakaryocytes. Little is known about the clinical course of this disease in pregnancy, because it usually occure in the late reproductive and menopausal years. We report one case of essential thrombocythemia diagnosed in the first trimester of pregnancy. A 32-year old woman (gravida 3, para 2) visited our hospital because of her poor obstetric history. In her first pregnancy, she aborted spontaneously. In the second, she delivered prematurely at 36 weeks of gestation. In the third pregnancy, she experienced abruptio placentae and DIC at 28 weeks of gestation. And she was given a 2, 000 ml blood transfusion. In our hospital, her platelet count was 84.7×10<SUP>4</SUP>/mm<SUP>3</SUP> and she was diagnosed as having a twin pregnancy at 9 weeks of geatation by ultrasonography. At the moment antiplatelet therapy (aspirin 30 mg and dipyridamole 150 mg daily) was started. She was hospitalized at 28 weeks of gestation because her platelet count was continuously greater than 100×10<SUP>4</SUP>/mm<SUP>3</SUP>. From that time, heparin (10, 000 i.u. daily) was intravenously administered to her. At 34 and 6/7 weeks of gestation, two healthy boys of 2350 gm and 2328 gm were born by cesarean section. The 1-and 5-minute Apgar scores were 6 and 9 in the first boy, 3 and 8 in the second boy. The placenta showed large thrombosis and ischemia. Her platelet count rose to 342×10<SUP>4</SUP>/mm<SUP>3</SUP> 3 weeks after delivery. From the result of our case of essential thrombocythemia in pregnancy, antiplatelet therapy may be useful for the treatment in this disease.
- 近畿産科婦人科学会の論文
近畿産科婦人科学会 | 論文
- 当院における卵巣粘液性腺癌の治療経験の検討
- 婦人科癌末期の難治性イレウスに対する減圧目的の経皮的内視鏡的胃瘻造設について
- 子宮体癌の保存的治療後妊娠での前置癒着胎盤に対し内腸骨動脈バルーン留置下で帝王切開および子宮全摘術を施行した1例
- 当科の卵巣粘液性腺癌の治療成績 : ─リンパ節郭清の適応についての考察
- 妊娠糖尿病を合併した高度肥満妊婦の分娩誘発の1例