切迫流産症状の定量化とその予後の予測に関する統計的検討

概要

論文の詳細を見る
The preterm delivery is the main cause of neonatal death. In the present investigation, the obstetrical signs such as uterine contraction, cervical dilatation, cervical effacement, station of the presenting part, genital bleeding, formation of forbag, and rapture of membranes were classified into four groups, viz. 0-3 points, and the total of these scores were corrected according to gestational ages, and other obstetrical histories and/or complications. Total score 7.2±0.7(mean±SEM, n=20) in patients who deliverd premature infants was significantlly higher than that (4.0±0.5, n=61) in patients who had term deliveries.Approximately half of the patients who showed the corrected total score higher than 7 points resulted in deliveries of premature babies, while only 1 case out of 38 patients (3%) with scores less than 4 points resulted in a preterm delivery.From the results of the present investigation it was indicated that almost all of preterm labors which show total score lower than 4 points can be arrested by the treatment with rest and oral administrations of β-stimulant (isoxsuprine), and that patients who show scores higher than 7 points should be treated more intensively with β-stimulant more specific to β2-receptor than isoxsuprine, in combination with the administration of glucocorticoid to enhance the fetal lung maturation.
近畿産科婦人科学会の論文