Effect of S-Self onated Human Immunoglobulin in Prevention of Post-Transfusion Hepatitis

概要

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In obstetrics and gynecology, operations such as the operation for uterine cervical cancer often need blood transfusion. Patients are often suffered more severely in post-transfusion hepatitis than in their original diseases. It has been a serious problem to prevent post-transfusion hepatitis.In this study S-sulfonated human immunoglobulin was examined in order to prevent post-transfusion hepatitis. In 1981 22 patients were received blood transfusion and immunoglobulin (5, 000mg intravenously). Two cases (9.1%) were diagnosed as hepatitis, and 2 cases (9.1%) as suspicion of hepatitis. On the other hand, 22 patients were received only blood transfusion in 1979 and 1980. Five cases (22.7%) were diagnosed as hepatitis, and 4 cases (18.2%) as suspicion of hepatitis. It was suggested that S-sulfonated human immunoglobulin may be effective in preventing post-transfusion hepatitis.
近畿産科婦人科学会の論文