Diabetes Insipidus with Eclampsia: A Case Report

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Diabetes insipidus in association with pregnancy is extremely rare, and has been reported only about 100 cases in foreign literatures and 26 cases in Japan.In this paper, one case of diabetes insipidus with pregnancy we have experienced lately is reported. Furthermore, literatures in Japan are reviewed and concomitant influences of pregnancy and diabetes insipidus are discussed.Case report:H. I., a 23-year-old Japanese female, gravida 1, para 0-0-0-0, who was diagnosed diabetes insipidus at 3 years old, visited our hospital at the 12th week of pregnancy. There were no abnormal findings except for slight aggravation of polyuria and polydipsia until the 38th week of pregnancy when preeclamptic signs appeared. At 39th week pregnancy, she had abruptly eclamptic attack during oxytocin infusion for premature rupture of the membranes. Thereafter, a mature female infant (3480g, Apgar's score 9) was immediately delivered by abdominal cesarean section under the general anesthesia (GOF) without further disturbances. In puerperium, polyuria with polydipsia soon returned to the state at early pregnancy, and toxemic signs disappeared within one week after delivery.
近畿産科婦人科学会の論文