Diagnostic Use of the LH-RH Test on Pathogenetic Analysis in Amenorrhea
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概要
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Synthetic luteinizing hormone releasing hormone (LH-RH), 100μg was administered intramuscularly to patients with variety of diseases of the hypothalamic-pituitary-gonadal axis. Plasma LH and FSH were measured by RIA using double antibody method, in which 2nd IRP-HMG was employed as standard reference preparation. After the administration of LH-RH, plasma LH and FSH values changed characteristically in hypothalamic, pituitary and gonadal diseases. Then the patients with 1st grade amenorrhea and 2nd grade amenorrhea were examined individually. The results suggest that in 1st grade amenorrhea there are both hypothalamic and gonadal hypofunctional amenorrhea, and in 2nd grade amenorrhea there are hypothalamic, pituitary and gonadal hypofunctional amenorrhea. Therefore, LH-RH test is able to correctly classify the patients with amenorrhea so that appropriate therapy for the specific condition can be instituted
- 近畿産科婦人科学会の論文
近畿産科婦人科学会 | 論文
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