Management of Cervical Carcinoma Associated with Pregnancy:Our 14 Cases and Reviewing the Literatures Concerning to the Management of Cervical Carcinoma, Especially Non-Invasive Carcinoma, Associated with Pregnancy

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Fourteen patients with cervical carcinoma associated with pregnancy, including three cases of carcinoma in situ, were seen at Osaka University Hospital between 1963 and 1975. All patients, except for one with a biopsy diagnosis of carcinoma in situ who was followed up and gave birth of full term baby, were treated with primary surgery. Radical hysterectomy with lymphadenectomy was performed in five patients (one with carcinoma in situ, two with stage Ib and two with stage IIb). Radical hysterectomy with lymphadenectomy and radiation therapy were performed in 6 patients (three with stag Ib, one with stage IIa and two with stage IIb). One patient with a conization diagnosis of carcinoma in situ was treated with simple hysterectomy after dilatation and curettage.Japanese reports of carcinoma in situ of the cervix associated with pregnancy was very few, in comparison with the reported incidence in the English literature. This may be due to the lack of routine cervical cytologic screening during the prenatal period, which was not usually done in Japan. This suggests that routine cervical cytologic screening warrants more consideration as one of the prenatal examination. Furthermore, there should be more reports to clarify the management of the carcinoma in situ associated with pregnancy.
近畿産科婦人科学会の論文