Intracavity Chemotherapy for Two Dogs with Malignant Mesothelioma.

概要

論文の詳細を見る
Intracavity chemotherapy was performed in two dogs with malignant mesothelioma. One dog (dog 1) was presented with marked pleural effusion and diagnosed on cytology of the fluid. The patient received three doses of intrapleural carboplatin, and was induced to complete remission. The dog showed recurrence at 639 days after the first admission, when pleural effsion again appeared. The other dog (dog 2) was presented with abdominal effusion, and was definitively diagnosed by exploratory laparotomy. Carboplatin was infused intraperitoneally. Then the general condition became better, however marked pleural effsion appeared. The dog recieved intracavital (both peritoneal and pleural) carboplatin or doxorubicin to control the effusion, inducing partial remission. The patient died at 268 days after the first admission. Intracavity chemotherapy may be effective to control of malignant mesothelioma.
獣医麻酔外科学会の論文