Rapid Inhalation Induction of Anesthesia with 5% Isoflurane or Sevoflurane in Dogs.

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Rapid inhalation induction of anesthesia (RI) using 5 % isoflurane or sevoflurane with or without 67% of nitrous oxide (OI, GOT, OS and GOS) was evaluated by compaing the movements, induction and intubation time, and the cardiovascular effects in 24 beagle dogs. Induc tion time of anesthesia (223.7±29.2 sec) in OI group was significantly shorter than that in OS group (310.2±33.9 sec) . In addition, induction of anesthesia was more rapid and smoother with the use of nitrous oxide (GOT: 206.2±24.4 sec, GOS: 260.8±22.2 sec) . All the dogs of any groups showed various degree of movements during induction. However, in GOT group, movements in half of the dogs were minimal. The changes in cardiac parameters after the beginning of inhalation was remarkable, especially in heart rate. However, stabilization on circulatory and respiratory function under the maintenance level (1.5 MAC) could be attained in 10 min. Therefore, GOI is the most practical method for RII in dogs wihtout undesired effects on the airway when the maximum scale of the commercial vaporizer (5%) was used.
獣医麻酔外科学会の論文