Skull base surgery-statistical analysis for 93 cases collected from study group of cancer research from the ministry of health and welfare.

概要

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This study is on-going as Group Study supported by Grant-in-Aid for Cancer Research from the Ministry of Health and Welfare of Japan. Ninety-three cases were collected from 8 institutions, and were analyzed. About 89% of the patients have malignant tumors of the nose and paranasal sinuses. As for the histologic type, squamous cell carcinoma is most common in 49 cases, followed by olfactory neuroblastoma in 11, adenoid cystic carcinoma in 10, and so on. Sixty-three patients had no prior treatment. In terms of craniotomy, we performed frontal craniotomy in 30 cases, fronto-temporal craniotomy in 30, and so on. As for repair of dura mater, fascia lata was used in 24 cases, then pericranial flap in 13, and galeopericranial flap in 11. For reconstruction of the skull base and the face, free rectos abdominis flap was most commonly used in 59 cases. The 5-year survival was 40% for all the patients, 45% for squamous cell carcinoma, and 50% for adenoid cystic carcinoma. The results obtained were very encouarging. The incidence of surgical complication was 36%.
日本頭頸部癌学会の論文